Table 4. Association of the HGK methylation frequencies with OGTT glucose levels in three sub-populations (univariate linear regression analyses).
All | Sub-population | |||
---|---|---|---|---|
♂Waist = 91.8 ± 8.3 cm ♀Waist = 84.8 ± 10.0 cm n = 163 (130 men) | BMI ≤ 23 ♂Waist = 82.1 ± 6.3 cm ♀Waist = 74.5 ± 2.9 cm n = 38 (29 men) | 23 < BMI ≤ 27 ♂Waist = 90.8 ± 4.5 cm ♀Waist = 82.7 ± 5.5 cm n = 72 (58 men) | 27 < BMI ♂Waist = 99.8 ± 5.0 cm ♀Waist = 97.0 ± 6.7 cm n = 53 (43 men) | |
Pearson correlation coefficient | OGTT glucose levels | |||
Pos. 1 | 0.562*** | 0.686*** | 0.512*** | 0.469* |
Pos. 2 | 0.688*** | 0.801*** | 0.655*** | 0.652*** |
Pos. 3 | 0.600*** | 0.740*** | 0.553*** | 0.536*** |
Pos. 4 | 0.539*** | 0.695*** | 0.507*** | 0.448** |
Pos. 5 | 0.564*** | 0.647*** | 0.522*** | 0.554*** |
Pos. 7 | 0.557*** | 0.658*** | 0.546*** | 0.485*** |
Pos. 8 | 0.595*** | 0.709*** | 0.546*** | 0.585*** |
Pos. 9 | 0.689*** | 0.792*** | 0.630*** | 0.709*** |
Pos. 10 | 0.513*** | 0.603*** | 0.531*** | 0.410** |
The methylation frequencies from figure 2C and OGTT glucose levels from three sub-populations were analyzed using Pearson correlation/univariate linear regression. Pos., position. BMI, body mass index. Waist, waist circumference. *P value < 0.05; ** P value < 0.01; *** P value < 0.001.