Skip to main content
. 2015 Dec 22;7(10):11424–11433. doi: 10.18632/oncotarget.6717

Figure 3. Histone modifications were changed in metaplastic acini and pancreatic tumor cells.

Figure 3

(A) Chromatin-immunoprecipitation (ChIP) followed by RT-PCR was performed in acini, 3D-ADMs and tumor cells with antibodies against H3K4me3 and H3K27me3 and the analysis of the Ptf1a, Rbpj and Rbpjl promoter. (B) Direct comparison of H2AK119ub enrichment in acini, 3D-ADMs and tumor cells was assessed by ChIP-RT-PCR. All ChIP-RT-PCR data are calculated as fold enrichment over IgG control and are represented as mean ± SEM (n = 3–5).