Table 1. Correlations between miR-150 expression and clinicopathological characteristics in 84 patients with HCC.
| Characteristics | n | miR-150 expression | p-values | |
|---|---|---|---|---|
| High | Low | |||
| All case | 84 | 42 | 42 | |
| Gender | ||||
| Male | 64 | 30 (46.9%) | 34 (53.1%) | 0.306 |
| Female | 20 | 12 (60.0%) | 8 (40.0%) | |
| Age | ||||
| ≥50 | 43 | 23 (53.5%) | 20 (46.5%) | 0.513 |
| <50 | 41 | 19 (46.3%) | 22 (53.7%) | |
| Liver cirrhosis | ||||
| Presence | 60 | 27 (45.0%) | 33 (55.0%) | 0.147 |
| Absence | 24 | 15 (62.5%) | 9 (37.5%) | |
| Tumor size (cm) | ||||
| >5 | 41 | 16 (39.0%) | 25 (61.0%) | 0.049* |
| ≤5 | 43 | 26 (60.5%) | 17 (39.5%) | |
| Tumor number | ||||
| Single | 61 | 32 (52.5%) | 29 (47.5%) | 0.463 |
| Multiple | 23 | 10 (43.5%) | 13 (56.5%) | |
| Differentiation | ||||
| High | 59 | 33 (55.9%) | 26 (44.1%) | 0.095 |
| Low | 25 | 9 (36.0%) | 16 (64.0%) | |
| Venous invasion | ||||
| Yes | 31 | 11 (35.5%) | 20 (64.5%) | 0.042* |
| No | 53 | 31 (58.5%) | 22 (41.5%) | |
| Metastasis | ||||
| Yes | 19 | 5 (26.3%) | 14 (73.7%) | 0.019* |
| No | 65 | 37 (56.9%) | 28 (43.1%) | |
| TNM stage | ||||
| I + II | 46 | 27 (58.7%) | 19 (41.3%) | 0.079 |
| III + IV | 38 | 15 (39.5%) | 23 (60.5%) | |
*
Statistically significant difference; TNM: T, tumor; N, lymph node; M, distant metastasis.