Table 2. Univariate and multivariate Cox regression analyses of overall survival in 84 patients with HCC.
Tumor characteristic | HR (95% CI) | p-value |
---|---|---|
Univariate Analysis (Cox: Enter) | ||
Gender(Female / Male) | 1.158(0.640-2.095) | 0.628 |
Age(<50 / ≥50) | 1.036(0.634-1.691) | 0.889 |
Liver cirrhosis(Absence / Presence) | 1.494(0.848-2.633) | 0.165 |
Tumor size (≤5cm / >5cm) | 1.543(0.942-2.527) | 0.085 |
Tumor number(Single / Multiple) | 1.588(0.926-2.722) | 0.093 |
Differentiation(High / Low) | 1.587(0.939-2.681) | 0.084 |
Venous invasion(− / +) | 6.880(3.912-12.102) | <0.001* |
Metastasis(− / +) | 10.115(4.949-20.671) | <0.001* |
TNM stage(I, II / III, IV) | 6.427(3.642-11.343) | <0.001* |
miR-150 (Low / High) | 2.363(1.429-3.907) | 0.001* |
Multivariate Analysis (Cox: Forward LR) | ||
Metastasis(− / +) | 3.413(1.593-7.315) | 0.002* |
TNM stage(I, II / III, IV) | 4.888(2.562-9.326) | <0.001* |
miR-150 (Low / High) | 2.048(1.209-3.468) | 0.008* |
Statistically significant difference; CI: confidence interval.