Table 2. Kaplan-Meier method and Cox proportional hazards model analysis of associations between the genotypes of XPG and CRC prognosis.

Variants	10 years OS					10 years PFS
	event	Median (months)	Log-rank P	HR (95% CI)	P a	event	Median (months)	Log-rank P	HR (95%CI)	P b
rs2094258
TT	83	106.067		1.000		76	87.667		1.000
CT	254	21.267	0.357	0.973 (0.747, 1.268)	0.842	208	98.633	0.169	0.85 (0.655, 1.108)	0.232
CC	265	119.800	0.945	0.942 (0.724, 1.223)	0.649	227	83.967	0.728	1.019 (0.785, 1.323)	0.889
CT/CC	519	119.800	0.600	0.978 (0.865, 1.106)	0.722	435	92.033	0.363	0.964 (0.854, 1.090)	0.561
rs2296147
CC	25	20.067		1.000		18	118.067		1.000
CT	200	119.800	0.392	1.381 (0.837, 2.276)	0.206	178	84.867	0.024	1.780 (1.093, 2.898)	0.021
TT	377	119.867	0.258	1.492 (0.915, 2.433)	0.108	315	89.567	0.025	1.740 (1.080, 2.803)	0.023
CT/TT	577	119.800	0.267	1.205(0.946,1.535)	0.131	493	88.500	0.020	1.324 (1.046, 1.667)	0.020
rs751402
AA	83	119.867		1.000		76	83.867		1.000
AG	263	119.800	0.489	0.953 (0.733, 1.240)	0.721	216	89.133	0.384	0.851 (0.655, 1.107)	0.851
GG	256	117.800	0.567	0.893 (0.688, 1.161)	0.399	219	92.033	0.521	0.830 (0.639, 1.080)	0.830
AG/GG	519	119.800	0.478	0.960 (0.850, 1.085)	0.515	435	91.233	0.414	0.917 (0.811, 1.036)	0.165
rs873601
AA	155	117.800		1.000		144	85.300		1.000
AG	286	119.800	0.347	1.028 (0,831, 1.272)	0.799	227	92.900	0.119	0.856 (0.694, 1.056)	0.856
GG	161	119.867	0.822	0.994 (0.780, 1.267)	0.964	140	93.267	0.502	0.969 (0.766, 1.226)	0.969
AG/GG	447	119.800	0.574	1.008 (0.912, 1.113)	0.877	367	93.267	0.162	0.946 (0.859, 1.043)	0.265

CRC, colorectal cancer; HR, hazard ratio; CI, confidence interval; OS, overall survival; PFS, progression-free survival.

^aP values were calculated after adjustment for BMI, dukes stage, recurrence/metastasis status and therapeutic response.

^bP values were calculated after adjustment for age and dukes stage.