Table 3. Two-sample t-test (4 df) with Holm-Bonferroni correction comparing ancestral against evolved lineages.
Accumulation | Within-host fitness | |||||
---|---|---|---|---|---|---|
Genotype | Lineage | t | P | t | P | |
2 NIb copies | TEV-NIb1-NIb9 | 9WL1 | −11.744 | <0.001a | −3.101 | 0.036 |
9WL2 | −14.697 | <0.001a | −5.610 | 0.005a | ||
9WL3 | −9.690 | 0.001a | −3.663 | 0.022 | ||
9WL4 | −27.962 | <0.001a | −10.713 | <0.001a | ||
9WL5 | −29.966 | <0.001a | −2.991 | 0.040 | ||
TEV-NIb2-NIb9 | 9WL1 | −9.305 | 0.001a | −4.849 | 0.003a | |
9WL2 | −3.284 | 0.030a | −4.358 | 0.012a | ||
9WL3 | −5.600 | 0.005a | −12.814 | <0.001a | ||
9WL4 | −8.222 | 0.001a | −5.348 | 0.006a | ||
9WL5 | −8.832 | 0.001a | −1.405 | 0.233 | ||
TEV | 9WL1 | 1.3475 | 0.249 | −4.836 | 0.008a | |
9WL2 | −0.2692 | 0.801 | −2.549 | 0.063 | ||
9WL3 | −0.4693 | 0.663 | −3.542 | 0.024 | ||
9WL4 | −0.5268 | 0.626 | −1.782 | 0.149 | ||
9WL5 | −0.7859 | 0.476 | −4.028 | 0.016 | ||
1 NIb copy, alternative position | TEV-NIb1-ΔNIb9 | 9WL1 | −1.521 | 0.203 | −0.395 | 0.713 |
9WL2 | −6.133 | 0.004a | 15.041 | <0.001a | ||
9WL3 | −2.534 | 0.064 | −0.515 | 0.634 | ||
9WL4 | −9.322 | 0.001a | 19.454 | <0.001a | ||
9WL5 | −7.363 | 0.002a | 3.986 | 0.016 | ||
9WL6 | −8.738 | 0.001a | 2.652 | 0.057 | ||
9WL7 | −5.670 | 0.005a | 17.220 | <0.001a | ||
TEV-NIb2-ΔNIb9 | 9WL1 | −16.224 | <0.001a | 3.139 | 0.035 | |
9WL2 | −11.531 | <0.001a | 0.805 | 0.466 | ||
9WL3 | −16.134 | <0.001a | 4.564 | 0.010 | ||
9WL4 | −9.068 | 0.001a | −0.989 | 0.379 | ||
9WL5 | −13.961 | <0.001a | −0.502 | 0.642 | ||
9WL6 | −14.943 | <0.001a | −3.544 | 0.024 | ||
9WL7 | −4.320 | 0.012a | 2.374 | 0.077 | ||
TEV | 9WL1 | 1.377 | 0.241 | −3.311 | 0.030 | |
9WL2 | 0.986 | 0.380 | −2.152 | 0.098 | ||
9WL3 | 0.476 | 0.659 | −1.674 | 0.170 | ||
9WL4 | 0.908 | 0.415 | −1.642 | 0.176 | ||
9WL5 | 1.464 | 0.217 | −1.867 | 0.135 | ||
9WL6 | 0.621 | 0.569 | −2.388 | 0.075 | ||
9WL7 | 0.497 | 0.646 | −2.865 | 0.046 |
Significant after Holm-Bonferroni correction.