Figure 4.

Deletion of MNN10, PPN1, RSV167, TPS1, and UBP3 decreases proliferation rate of many disomic yeast strains. Doubling times of the indicated strains were determined as described in Figure 2. Cells were grown in either YPD medium (B–E) or YEP containing 2% raffinose 2% galactose (A) as deletion of TPS1 causes lethality in glucose. Arrows indicate disomes the doubling time of which increases more upon gene deletion than does that of wild type.