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. 2016 Feb 8;202(4):1289–1297. doi: 10.1534/genetics.115.179846

Table 4. Power (%) of each test under the alternative hypothesis of interaction effect, γ=0.2.

Power (%)
Probit Logit Log penetrance
Tests d.f. p=10% p=1% p=0.1% p=10% p=1% p=0.1% p=10% p=1% p=0.1%
A. β1=β2=0
SI 4 43.94 83.49 96.46 54.29 68.75 69.86 71.03 69.31 69.55
ImAP 4 35.20 87.53 99.31 47.71 66.90 68.65 68.71 68.02 69.22
ImAP2 4 20.45 55.13 80.91 27.15 38.39 40.17 39.90 39.37 39.66
ImAP3 4 88.76 99.89 100.00 95.39 99.06 99.05 99.12 99.17 99.24
CLRPC1 4 33.32 70.24 89.30 41.58 54.65 55.88 56.04 55.88 56.24
SC 1 65.84 95.04 99.50 75.65 87.13 87.63 88.08 87.67 87.69
CLRPC2 1 52.74 87.64 97.25 62.82 76.15 76.59 77.46 76.29 77.31
TC 1 69.70 97.16 99.87 79.67 90.23 90.71 91.21 90.97 90.81
B. β1=β2=0.2
SI 4 13.77 27.50 43.71 34.79 62.81 66.54 67.22 67.67 67.56
ImAP 4 15.52 52.95 89.41 83.43 99.50 99.70 99.74 99.77 99.65
ImAP2 4 6.10 12.71 20.90 16.72 35.99 38.62 40.02 40.18 40.42
ImAP3 4 83.47 99.83 100.00 100.00 100.00 100.00 100.00 100.00 100.00
CLRPC1 4 11.73 21.84 33.07 26.71 49.92 51.99 53.24 53.77 53.41
SC 1 23.14 47.00 65.28 53.61 82.69 85.60 86.04 85.50 85.58
CLRPC2 1 18.28 36.36 52.98 42.39 71.19 73.90 74.92 74.95 74.57
TC 1 26.74 57.45 81.22 70.72 94.66 96.09 96.16 96.22 96.22

Results are based on 10,000 simulated data sets. p, disease prevalence in the population.