Figure 7.13.10.

Single-particle EM 3D-reconstruction from 2D-projections. A set of 2D-projections (four in this case) is depicted along rendered iso-surfaces. The Fourier transform of a 2D-projection is equivalent to a central section in the 3D-FT of a molecule. Once a sufficient number of sections are available, the complete 3D-transform can be generated and inverse-transformed into a 3D-density map (bottom). Reprinted from Saibil (2000) with permission from the International Union of Crystallography.