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Comparison of adenovirus structures obtained by X-ray crystallography and cryo-EM at 3.5 Å resolution. (A) Structure and electron density of a segment of protein VIII obtained by X-ray crystallography (Reddy et al., 2010; Reddy and Nemerow, 2014). (B) The corresponding segment and electron density obtained by cryo-EM (Liu et al., 2010). Image courtesy of Prof. Vijay Reddy (The Scripps Research Institute).
