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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Dev Biol. 2016 Apr 27;415(1):87–97. doi: 10.1016/j.ydbio.2016.04.018

Figure 3. Inhibition of cell death in the CNS results in increased ventral muscle fibers.

Figure 3

The broad-spectrum caspase inhibitor p35 was used to inhibit cell death exclusively in the developing CNS. A) UAS-p35 alone had wild type fiber numbers B) expression of p35 with wor-Gal4 rescues embryonic abdominal NBs, and increases muscle fiber numbers. C) Combining wor-Gal4 with elav-Gal4 rescues both NBs and neurons, and results in a significant increase in fiber number. D) Fiber number counts (x̄ shown as bar). elav-Gal4 alone results in an increase in fiber number, but both elav>p35 and wor>35 increased fiber number slightly more, and when combined the two drivers together showed a significant increase (* p<0.05 vs. elav-Gal4, wor-Gal4). Animals/genotype UAS-p35 n=7, elav-Gal4 wor-Gal4 n=4, elav>p35 n=8, wor>p35 n=7, elav wor>p35 n=4.