Skip to main content
. Author manuscript; available in PMC: 2016 Dec 10.
Published in final edited form as: Science. 2016 Jun 10;352(6291):1330–1333. doi: 10.1126/science.aaf4417

Fig. 1. Structure of TAP-RPo.

Fig. 1

(A) Nucleic-acid scaffold. Pink, nontemplate strand; red, template strand; magenta, UpCpGpA; violet, extended -10 element; blue, -10 element; light blue, discriminator element.

(B-C) TAP-RPo (ribbons in B; surfaces in C; β′ nonconserved region omitted for clarity). Cyan, TAP; yellow, σ; white, green, gray, and dark gray, RNAP αNTD, αCTD, β, and β′. Other colors as in A. Dashed lines, αNTD-αCTD linkers.

(D) Comparison of TAP-DNA in TAP-RPo (colors as in B-C) to CAP-DNA (gray; 6).

(E) Comparison of transcription bubble and downstream dsDNA in TAP-RPo (colors as in B-C) to corresponding DNA segments in RPo (cyan; 7).