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. 2016 Jun 6;17(Suppl 5):181. doi: 10.1186/s12859-016-1040-7

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© Chouvardas et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — a Global (regulatory/functional) network for the human test case colorectal cancer. It includes the regulatory network extracted (as described in Fig. 1) and the functional categories (GOs and Kegg pathways) which are enriched (P-value Cutoff = 0.05) in DE genes. Node color and size and node label font size are visualized based on Betweenness centrality, which is an indicator of the centrality of a node in a network. b Regulatory network for the human test case of colorectal cancer. Node color and size and node label font size are visualized based on betweenness centrality, which is a measure of the centrality of a node in a network