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. 2016 Jun 6;17(Suppl 5):174. doi: 10.1186/s12859-016-1045-2

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© Moschen et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Integrated network of hubs metabolites and transcription factors. Pearson correlation analysis of 24 selected hubs metabolites and the list of 82 TFs statistically significant during senescence. Correlations with p-value < 0.0001 were selected and visualized in Cytoscape [46] by degree (node size and color) and edge weight (edge size and color)