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. 2016 Jun 13;11(6):e0157388. doi: 10.1371/journal.pone.0157388

Table 3. Retinal layer thicknesses measured by spectral domain optical coherence tomography in both eyes of all patients with unilateral traumatic optic neuropathy.

All measurements were significantly smaller in TON eyes than those in unaffected eyes. (Wilcoxon sign rank test).

Variable Affected eyes (n = 29) Unaffected eyes (n = 29) p-value*
Mean ±SD (%)a Mean ±SD
Thicknessm)
cpRNFL
  Temporal 59±25 (23%) 77±14 <0.01*
  Nasal 51±26 (20%) 64±15 <0.01*
  Superior 101±35 (22%) 129±17 <0.01*
  Inferior 98±37 (21%) 124±16 <0.01*
Entire retina
Inner locations
  Inner temporal 278±10 (3%) 289±22 <0.01*
  Inner nasal 286±20 (3%) 296±26 <0.01*
  Inner superior 290±18 (3%) 299±21 <0.01*
  Inner inferior 291±17 (3%) 298±21 0.03*
Outer locations
  Outer temporal 319±22 (4%) 333±15 <0.01*
  Outer nasal 335±30 (6%) 358±22 <0.01*
  Outer superior 336±28 (6%) 356±17 <0.01*
  Outer inferior 327±29 (5%) 344±18 <0.01*
fRNFL
Outer locations
  Outer temporal 14±6 (12%) 16±3 <0.01*
  Outer nasal 20±10 (29%) 28±5 <0.01*
  Outer superior 27±14 (32%) 40±5 <0.01*
  Outer inferior 27±12 (36%) 42±6 <0.01*
GCIPL
Inner locations
  Inner temporal 33±12 (25%) 44±14 <0.01*
  Inner nasal 35±12 (26%) 47±13 <0.01*
  Inner superior 37±16 (26%) 50±12 <0.01*
  Inner inferior 38±15 (25%) 51±12 <0.01*
Outer locations <0.01*
  Outer temporal 72±21 (20%) 90±9 <0.01*
  Outer nasal 74±23 (24%) 97±13 <0.01*
  Outer superior 71±19 (20%) 89±9 <0.01*
  Outer inferior 73±17 (19%) 90±9 <0.01*

SD, standard deviation; cpRNFL, peripapillary retinal nerve fiber layer; fRNFL, foveal retinal nerve fiber layer; GCIPL, ganglion cell layer and inner plexiform layer

a % change of the affected eye compared with the contralateral eye

* p < 0.05, Wilcoxon sign-rank test