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. 2016 Jun 13;11(6):e0157265. doi: 10.1371/journal.pone.0157265

Table 2. EZH2 increased cholesterol levels in THP-1-derived foam cells via DNA methylation.

control 5-Aza-dC EZH2 5-Aza-dC+EZH2
TC (mg/g protein) 503±28 391±32* 594±37# 508±29
FC (mg/g protein) 190±27 138±31* 242±24# 191±33
CE (mg/g protein) 314±32 174±26* 454±35# 312±32
CE/TC (%) 61.9 44.5 76.4 61.4

TC: total cholesterol, FC: free cholesterol, CE: cholesterol ester.

*: P<0.05 vs. control

#: P<0.05 vs. 5-Aza-dC+EZH2.