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. 2016 Jun 13;11(6):e0157380. doi: 10.1371/journal.pone.0157380

Table 1. Incidence rate ratio (95% confidence interval) of different activities for treatment group compared to control group: mixed effects poisson regression analysis that adjusted for offspring weight, gender, random selection, and testing time and day.

P<0.008 was considered significant.

TLMA Rear Central Peripheral Fine Total Ambulation
Treatment group (vs. control group) Overall Unadjusted IRR (95%CI) P value 1.115 (0.951–1.308) P = .180 1.123 (0.903–1.396) P = .296 0.996 (0.788–1.258) P = .971 1.132 (0.962–1.333) P = .136 1.092 (0.945–1.262 P = .231 1.134 (0.953–1.350) P = .157
Overall Adjusted IRR (95%CI) P value 1.140 (0.989–1.315) P = .071 1.148 (0.939–1.403) P = .179 0.976 (0.777–1.225) P = .832 1.167 (1.007–1.352) P = .040 1.113 (0.979–1.266) P = .102 1.181 (1.007–1.385) P = .041
Adjusted IRR for Male Offspring (95% CI) P value 1.121 (0.934–1.569) P = .147 1.325 (1.012–1.737) P = .041 0.936 (0.685–1.279) P = .680 1.257 (0.980–1.611) P = .071 1.220 (1.020–1.460) P = .029 1.211 (0.978–1.499) P = .079
Adjusted IRR for Female Offspring (95% CI) P value 0.986 (0.797–1.219) P = 0.893 0.932 (0.697–1.246) P = .635 0.951 (0.734–1.233) P = .705 0.978 (0.782–1.234) P = .846 0.926 (0.777–1.102) P = .387 1.039 (0.818–1.320) P = .752

TLMA, total locomotor activity was calculated from addition of central and periphery gross motor activity and fine activity. N = 16/group.