Table 2.
Variable | Home-based (n = 53) | Supervised (n = 51) | Sertraline (n = 49) | Placebo (n = 49) | Active vs. Placebo | Exercise vs. Sertraline |
---|---|---|---|---|---|---|
Intima Medial Thickness, mm * | 0.65 (0.01) | 0.64 (0.01) | 0.63 (0.01) | 0.67 (0.01) | .037 | .291 |
Flow-Mediated Dilation, % * | 5.8 (0.5) | 6.9 (0.6) | 6.2 (0.6) | 4.8 (0.6) | .032 | .798 |
ASCVD Risk Score, 10-year % Risk (ranked) * | 4.6 (0.3) | 4.0 (0.3) | 4.0 (0.3) | 4.3 (0.3) | .049 | .741 |
Systolic Blood Pressure, mm Hg* | 122 (2) | 118 (2) | 117 (2) | 124 (2) | .012 | .245 |
Total Cholesterol, ng/ml | 209 (4) | 204 (4) | 215 (4) | 203 (4) | .134 | .047 |
High Density Lipoprotein, ng/ml | 55 (1) | 57 (1) | 55 (1) | 56 (1) | .894 | .534 |
Analyses are adjusted for age, sex, severity of depression, and the respective pretreatment level of each outcome. FMD analyses were also adjusted for baseline arterial diameter.
Active treatments differ from Placebo at P < .05. Values are derived from multiple imputation estimates based on the entire sample (n = 202). Complete data were available for 169 participants for the ASCVD risk score and its components (84%), 172 participants for flow-mediated dilation analyses (85%), and 168 for intima medial thickness analyses (83%).