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. Author manuscript; available in PMC: 2017 Jun 13.
Published in final edited form as: Integr Biol (Camb). 2016 Jun 13;8(6):720–728. doi: 10.1039/c6ib00027d

Figure 5. Mechanically primed hepatic stellate cells show reduced nuclear YAP/TAZ on stiff-to-soft hydrogels.

Figure 5

(A) Representative images and quantification of YAP/TAZ staining for freshly isolated stellate cells cultured for 7 days on soft hydrogels or glass. Blue: nuclei, Green: YAP/TAZ. (B) Representative images and quantification of YAP/TAZ staining for stellate cells cultured for 21 days total on soft hydrogels (soft static, dashed line) or mechanically primed stellate cells cultured for an additional 14 days on soft, stiff, or stiff-to-soft hydrogels. Blue: nuclei, Green: YAP/TAZ. (Dashed line: soft static control). ***: P < 0.001, significantly greater than other experimental groups. Scale bars: 20 μm. n > 26 cells per group