Mechanically isolated antral follicles were cultured with CAA, BAA, or IAA for 96 hours. Growth of follicles was recorded in micrometers every 24 hours and reported as percent change compared to the follicle size at the beginning of treatment (0 hour = 100%). DMSO = dimethylsulfoxide, CAA = chloroacetic acid, BAA = bromoacetic acid, IAA = iodoacetic acid. Data represent means ± SEM from at least three separate experiments. Asterisks (*) represent significant differences from DMSO control at each time point (p ≤ 0.05).