Table 1.
Kinetics of parasitemia and antibody titers in the rhesus macaques infected with B. microti during the three phases of the study
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|---|---|---|---|
| Hamster-passaged B. microti
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Monkey-passaged B. microti
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| Screening Test | Phase 1 | Phase 2 | Phase 3 |
| qPCR parasitemia* | |||
| First detection | 35 | 4 | 4 |
| Peak detection | 56–63 | 14–21 | 35 |
| Blood smear parasitemia* | |||
| First detection | 49 | 4 | 21 |
| Peak detection | 56–63 | 14–21 | 35 |
| IFA titer* | |||
| First response | 35–49 | 14 | 21 |
| Peak response | 56 | 21 | 35 |
*
Data correspond to respective study day(s) in the particular phase (Phase 1: monkeys RFl9 and RGc8; Phase 2: monkeys RLk10, RZz9, and RCq10; Phase 3: monkey RVf12)