Table 3.
Summary of the largest fold changes in gene expression for the higA mutant versus the isogenic Pseudomonas aeruginosa PA14 wild type strain. Both strains were grown to a turbidity of 2.0 at 600 nm in LB medium
| Genes | Fold change | Description |
|---|---|---|
| higB 28.0 toxin gene | ||
| Part of the pyoverdine locus (Ravel and Cornelis 2003) | ||
| PA2405 | 9.2 | Hypothetical protein |
| PA2404 | 8.0 | Hypothetical protein; membrane proteins |
| PA2408 | 7.0 | Probable ATP‐binding component of ABC transporter, membrane proteins |
| PA2403 | 5.7 | Hypothetical protein; membrane proteins |
| PA2406 | 5.3 | Hypothetical protein |
| PA2409 | 4.0 | Probable permease of ABC transporter, membrane proteins/transport of small molecules |
| PA2407 | 3.5 | Probable adhesion protein, motility and attachment |
| PA2410 | 3.5 | Hypothetical protein |
| Related to pyoverdine and iron transportation | ||
| PA2398_fpvA | 7.0 | Ferripyoverdine receptor/transport of small molecules |
| PA4675 | 5.3 | Probable TonB‐dependent receptor/transport of small molecules |
| PA0805 | 4.0 | Hypothetical protein |
| Pyochelin genes | ||
| PA4230_pchB | −9.2 | Salicylate biosynthesis protein PchB/transport of small molecules; secreted factors (toxins, enzymes, alginate) |
| PA4231_pchA | −7.5 | Salicylate biosynthesis isochorismate synthase/secreted factors (toxins, enzymes, alginate); transport of small molecules |
| PA4229_pchC | −6.1 | Pyochelin biosynthetic protein PchC/transport of small molecules; secreted factors (toxins, enzymes, alginate) |
| PA4226_pchE | −4.9 | Dihydroaeruginoic acid synthetase/transport of small molecules; secreted factors (toxins, enzymes, alginate) |
| PA4224_pchG | −4.9 | Hypothetical protein; membrane proteins |
| PA4228_pchD | −4.6 | Pyochelin biosynthesis protein PchD/transport of small molecules; secreted factors (toxins, enzymes, alginate) |
| PA4225_pchF | −4.0 | Pyochelin synthetase/transport of small molecules; secreted factors (toxins, enzymes, alginate) |
| PA4227_pchR | −2.6 | Transcriptional regulator PchR/transcriptional regulators |
| Pyochelin‐related genes and nearby genes to the pch operon | ||
| PA4221_fptA | −6.1 | Fe(III)‐pyochelin receptor precursor/transport of small molecules |
| PA4223 | −4.0 | Probable ATP‐binding component of ABC transporter/membrane proteins; transport of small molecules |
| PA4218 | −4.0 | Probable transporter/membrane proteins; transport of small molecules |
| PA4220 | −3.7 | Hypothetical protein |
| PA4219 | −3.5 | Hypothetical protein/membrane proteins |
| PA4222 | −3.2 | Probable ATP‐binding component of ABC transporter/transport of small molecules |
| PA0985_pyoS5 | −3.2 | Probable colicin‐like toxin/membrane proteins; secreted factors (toxins, enzymes, alginate) |