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Effect of crosslinking on alcohol responses in TM3-4 mutants. Tracings showing the effect of 22 mM butanol before and after application of 10 μM HgCl2 on EC5−10 glycine-induced currents in individual oocytes expressing wild-type (A) or A288C/Y410C (B) GlyRs. The upper bars indicate butanol pre-application.
