Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Mar 2;5(1):1–18. doi: 10.1007/s40119-016-0058-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PMC Copyright notice

Fig. 1 — In a, FXa forms a complex with FVa to allow for conversion of prothrombin to thrombin. In b, FXa inhibitor binds to FXa, preventing the conversion of prothrombin to thrombin. In c, FXa inhibitor binds to andexanet alfa rather than FXa, allowing for formation of thrombin. Gla Gamma-carboxyglutamic acid