Table 5.

Risk factors for development of acute skin reactions to radiation

Extrinsic
Total radiation dose
Fractionation schedule
Type of radiation
Quality of radiation beam
Concurrent chemotherapy
Antibiotics
Anti-tuberculosis medications

Intrinsic
Advanced age
Female sex
Obesity
Comorbidities (diabetes mellitus, connective tissue disease)
Chronic sun exposure
Radiosensitive disorders
Ataxia telangiectasia
Xeroderma pigmentosa
Previous breast reconstruction/implants
Nutritional status
Immunocompromised
Smoking