Table 7.

Preventions and treatments for acute cutaneous skin reactions to radiotherapy

Prevention	Level of evidence
Proper skin hygiene	Wash with mild soaps and lukewarm water to help maintain skin barrier
Protection of skin from additional trauma	Use of topical steroids; use before development of radiation dermatitis to slow progression to radiation dermatitis (Grade B) Oral Wobe-Mugus can decrease odds of developing radiation dermatitis (Grade C) Wear loose fitting clothing, avoid sun exposure, avoid metallic based topical products, use water based lanolin-free moisturizers

Treatment of	Level of evidence
Dry desquamation	Low- to mid-potency topical steroids; decrease progression and severity of itching, burning and irritation (Grade C) Use of hydrophilic moisturizers
Moist desquamation	Wound care management with hydrogel and hydrocolloid dressings
Radiation burns	Removal of necrotic debris and mesenchymal stem cell injections to area to increase healing Mesenchymal stem cell injections around lesions to enhance wound healing (Grade D)