Table 3.
Baseline characteristics of the included participants. The physical and biochemical data were collected at the screening visit. Data for compliance were collected at their first and final visits. The data are depicted as the means (standard deviation) and p values.
| Placebo | Simvastatin | ||
|---|---|---|---|
| N | 19 | 20 | |
| Physical data | Mean (SD) | Mean (SD) | p |
| Age (yrs.) | 25.5 (5.49) | 25.2 (6.30) | 0.86 |
| Weight (kg) | 80.4 (10.85) | 79.8 (11.55) | 0.99 |
| Height (m) | 1.84 (0.10) | 1.83 (0.06) | 0.86 |
| Body Mass Index (kg/m2) | 23.8 (2.47) | 23.7 (2.95) | 0.95 |
| Biochemical data | Mean (SD) | Mean (SD) | |
| Ferritin (μg/L) | 154.37 (80.44) | 135.95 (93.43) | 0.51 |
| Hemoglobin (mmol/L) | 9.42 (0.44) | 9.17 (0.63) | 0.16 |
| Iron (μmol/L) | 21.95 (5.20) | 23.55 (7.07) | 0.43 |
| Creatinine (μmol/L) | 91.74 (10.19) | 89.75 (11.31) | 0.57 |
| Total cholesterol (mmol/L) | 4.11 (0.75) | 4.10 (0.77) | 0.97 |
| HDL cholesterol (mmol/L) | 1.40 (0.17) | 1.46 (0.29) | 0.47 |
| LDL cholesterol (mmol/L) | 2.41 (0.69) | 2.32 (0.76) | 0.70 |
| Triglycerides (mmol/L) | 0.83 (0.52) | 0.85 (0.50) | 0.88 |
| Compliance | Mean (SD) | Mean (SD) | |
| Trial medicine administration (%) | 100 (0) | 98.9 (3.49) | 0.19 |
| Urine collection 1, before (%) | 99.7 (1.26) | 99.5 (1.51) | 0.66 |
| Urine collection 2, after (%) | 99.1 (3.16) | 99.2 (3.62) | 0.94 |