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. 2016 Jun 7;110(11):2419–2429. doi: 10.1016/j.bpj.2016.04.018

Table 1.

p7 Consensus Sequences for HCV Genotypes 1–4

Genotype p7 Protein Sequence
All ALENLVVLNAASAAGTHGILWFLVFFCAAWYVKGRLVPGATYSLLGLWPLLLLLLALPQRAYA

1 ALENLVLLNAASLAGTHGLVSFLVFFCFAWYLKGRWVPGAAYAVYGMWPLLLLLLALPQRAYA
1aa ALENLVILNAASLAGTHGLVSFLVFFCFAWYLKGRWVPGAVYAFYGMWPLLLLLLALPQRAYA
1b ALENLVVLNAASLAGAHGILSFLVFFCAAWYIKGRLVPGAAYALYGVWPLLLLLLALPPRAYA
1c ALENLIVLNAASLVGTHGIVPFFIFFCAAWYLKGKWAPGLAYSVYGMWPLLLLLLALPQRAYA

2 ALEKLVILHAASAASANGPLWFFIFFVAAWYIKGRVVPLATYSLLGLWSFLLLVLALPQQAYA
2aa ALEKLVVLHAASAASCNGFLYFVIFFVAAWYIKGRVVPLATYSLTGLWSFGLLLLALPQQAYA
2b ALEKLIILHSASAASANGPLWFFIFFTAAWYLKGRVVPVATYSVLGLWSFLLLVLALPQQAYA
2c ALEKLVILHAASAASSNGLLYFILFFVAAWCIKGRAVPMVTYTLLGCWSFVLLLMALPHQAYA

3 ALENLVTLNAVAAAGTHGIGWYLVAFCAAWYVRGKLVPLVTYSLTGLWSLALLVLLLPQRAYA
3aa ALENLVTLNAVAAAGTHGIGWYLVAFCAAWYVRGKLVPLVTYSLTGLWSLALLVLLLPQRAYA
3b AMENLVMLNALSAAGQQGYVWYLVAFCAAWHIRGKLVPLITYGLTGLWPLALLDLLLPQRAYA

4 ALSNLININAASAAGTHGFWYAIFFICIAWHVKGRLPAAATYAACGMWPLLLLLLMLPERAYA
4aa ALSNLININAASAAGAQGFWYAILFICIVWHVKGRFPAAAAYAACGLWPCFLLLLMLPYRAYA

p7 protein sequences after Carrère-Kremer et al. (19). Consensus sequences are shown in bold.

a

Sequences used in this study.