Table 3.
Predictors of quality of life using mixed effects modelling.
| β | Std. Error | t | p | ||
|---|---|---|---|---|---|
| Basic model | |||||
| Gender (Female) | 3.7 | 1.3 | 2.7 | 0.007 | ** |
| Education (Years) | −0.7 | 0.2 | −3.6 | <0.001 | *** |
| Age | −0.3 | 0.1 | −4.4 | <0.001 | *** |
| LED | 0.02 | 0.0 | 3.8 | <0.001 | *** |
| GDS-15 | 3.3 | 0.4 | 8.2 | <0.001 | *** |
| Time (Assessment) | −3.5 | 1.3 | −2.6 | 0.009 | ** |
| UPDRS III | 0.1 | 0.1 | 0.3 | 0.785 | |
| UPDRS III over Time | 0.2 | 0.0 | 5.1 | <0.001 | *** |
| GDS-15 over Time | −1.1 | 0.1 | −8.2 | <0.001 | *** |
| Basic model + MoCA | |||||
| MoCA | 0.2 | 0.3 | 0.8 | 0.448 | |
| MoCA over Time | −0.4 | 0.1 | −3.1 | 0.002 | ** |
| Basic model + Cognitive classification | |||||
| PD-MCI | 2.1 | 2.6 | 0.8 | 0.433 | |
| PDD | −16.6 | 10.9 | −1.5 | 0.129 | |
| PD-MCI over Time | 0 | 1.2 | 0 | 0.973 | |
| PDD over Time | 10.3 | 4.0 | 2.6 | 0.011 | * |
| Basic model + Factor scores | |||||
| Memory/executive function | 1.0 | 1.3 | 0.7 | 0.457 | |
| Attention | 1.9 | 1.3 | 1.5 | 0.13 | |
| Global Cognition | 0.1 | 1.3 | 0.0 | 0.971 | |
| Memory/executive function over Time | −1.1 | 0.6 | −1.6 | 0.107 | |
| Attention over Time | −2.3 | 0.7 | −3.5 | <0.001 | *** |
| Global Cognition over Time | −0.4 | 0.6 | −0.7 | 0.492 | |
* p < 0.05, ** p < 0.01, *** p < 0.001.
GDS-15 = Geriatric Depression Scale, UPDRS III = Movement Disorders Society-Unified Parkinson's Disease Rating Scale Part III, LED = Levodopa equivalent dose, MoCA = Montreal Cognitive Assessment, PD-MCI = PD-MCI classified using the Movement Disorder Society with 2 standard deviation (SD) cut off, PDD = Parkinson's disease dementia.