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. 2016 Aug;1857(8):1027–1038. doi: 10.1016/j.bbabio.2016.04.284

Table 3.

Gene annotations of the 62 anaerobic core families.

Cluster Annotation Comments
6079 radical_SAM_protein SAM methyltransferase
9248 radical_SAM_protein Pyruvate formate lyase activating enzyme EC:1.97.1.4; SAM methyltransferase
21,920 Radical_SAM_domain_protein rlmN; 23S rRNA methyltransferase [EC:2.1.1.192]; SAM
10,466 type_11_methyltransferase SAM methyltransferase
21,520 type_11_methyltransferase SAM methyltransferase
14,283 Methylase_involved_in… SAM methyltransferase
1662 50S_ribosomal_protein_L29 RP-L29, rpmC; large subunit ribosomal protein L29
1296 acetyl-CoA_decarbonylase/synthase… Acetyl-CoA decarbonylase/synthase complex subunit gamma [EC:2.1.1.245]
1321 acetyl-CoA_decarbonylase/synthase… Acetyl-CoA decarbonylase/synthase complex subunit delta [EC:2.1.1.245]
7851 ATP_synthase_subunit_c ATPVK, ntpK, atpK; V/A-type H +-transporting ATPase subunit K
4404 ferredoxin fer; ferredoxin
18,705 flavodoxin Flavodoxin
13,779 heterodisulfide_reductase_subunit_A… Heterodisulfide-reductase CoB CoM
14,009 heterodisulfide_reductase_subunit_C… Heterodisulfide reductase; CoM CoS
4789 membrane_bound_hydrogenase_subunit… Multicomponent Na +:H + antiporter
11,625 Membrane-bound_hydrogenase_MBH… Membrane-bound-hydrogenase antiporter subunit
11,548 L-glutamine_synthetase glnA, GLUL; glutamine synthetase [EC:6.3.1.2]; glutamine-synthetase
10,709 nitrogenase_iron-iron_accessory_protein… Iron–iron nitrogenase accessory protein AnfO
5364 acetyltransferase CoA acyl-CoA acetyltransferase
10,044 phenylacetate–CoA_ligase paaK; phenylacetate-CoA ligase [EC:6.2.1.30]; CoA phenylacetate-CoA-ligase
23,640 NADPH-dependent_FMN_reductase FMN FAD NADH NADH-dependent-FMN-reductase
10,494 NADPH-dependent_FMN_reductase NADH-dependent-FMN-reductase
4774 sugar_kinase Sugar-kinase
11,273 FeoA_family_protein feoA ferrous iron transport protein A
11,762 aldo/keto_reductase K07079; NADH aldo/keto-reductase
12,136 putative_ABC_transporter Putative ABC transport system permease protein
6304 citrate_transporter Citrate_transporter
16,010 cobalamin_biosynthesis_protein cbiN; cobalt/nickel transport protein; cobalamin
14,243 cytochrome_c_biogenesis… Cytochrome c-biogenesis transmembrane protein
1071 ApbE_family_lipoprotein K09740; hypothetical protein; ApbE_family_lipoprotein
6375 beta-lactamase_domain-containing_protein Beta-lactamase metal dependent
4311 deblocking_aminopeptidase E3.2.1.4; endoglucanase metal metallopeptidase
22,518 YcfA-like_protein hicA; mRNA interferase HicA [EC:3.1.-.-]; YcfA-like-protein
15,732 nucleotidyltransferase K07076; nucleotidyltransferase
4155 PP-loop_domain-containing… ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA; PP-loop
9988 regulatory_protein_MarR Regulatory-protein-MarR transcriptional-regulator
23,018 type_II_site-specific_deoxyribonuclease Type-II-restriction-enzyme type-II-site-specific-deoxyribonuclease
16,528 transposase,_IS4 Transposase
10,489 ATP-dependent_RNA_helicase CRISPR-associated-endonuclease/helicase Cas3; ATP-dependent
15,539 CRISPR-associated_protein… CRISPR-associated protein Cmr3
14,799 CRISPR-associated_protein… CRISPR-associated protein Csm1
18,976 helicase_domain_protein Helicase
20,220 helicase-like_protein Helicase
2237 xylose_isomerase_domain… Metal-dependent; xylose-isomerase-domain-containing-protein
20,694 xylose_isomerase_domain… Metal xylose-isomerase-domain-containing-protein
7805 putative_YgiT-type_zinc_finger Zinc zinc-finger domain

16 other protein families annotated as hypothetical proteins.