Skip to main content
. 2016 Jun 7;110(11):2293–2301. doi: 10.1016/j.bpj.2016.04.035

Figure 1.

Figure 1

Three-dimensional structure of the influenza A HA ectodomain in its prefusion (PDB: 2YPG) and postfusion (PDB: 1HTM) states (H3 subtype). The trimeric quaternary structure of HA is presented in a cartoon representation with the HA1 subunit in orange and the HA2 subunit in gray. The TMD is shown in blue (not part of the crystal structures). The B-loop region (shown in dark red) and residues 106–112 of HA2 (displayed in green) undergo secondary-structure changes upon a drop in pH, and the fusion peptide (purple) is anchored in the fused membrane.