Table 1.

Summary of H₂O₂-Mediated Inhibition of SOICR

	Persistent H2O2	Removal of H2O2	Posttreatment with DTT	Pretreatment with DTT
Time to loss of SOICR (minutes)	14.41 ± 0.74	17.23 ± 0.64a	18.15 ± 0.85b	12.32 ± 0.55, not significant
Loss of SOICR (% cells)	85.8 ± 6.89 n = 5	57.4 ± 8.38, not significant, n = 5	72.52 ± 10.04, not significant, n = 5	73.9 ± 11.7, not significant, n = 8

Values are mean ± SE. Time and percentage of cells experiencing complete inhibition of SOICR. Time is given from the application of H₂O₂. Means and statistical analysis were calculated from the number of assays performed (n = 5 or 8) Total cells per condition were: 234, 148, 188, and 203 for persistent removal of H₂O₂, posttreatment with DTT, and pretreatment with DTT, respectively.

^ap < 0.05

^bp < 0.01 versus persistent H₂O₂