Figure 2.

Individual differences in resting state functional connectivity are correlated with body composition (i.e., BMI and/or BFP), corrected for age and gender. (A) Previously defined regions of interest were taken from an anatomical atlas (Shirer et al., 2012) of three functionally distinct brain networks, including: all 19 nodes of the default mode network (DMN; red), all 12 nodes of the executive control network (ECN; green), and all 19 nodes of the salience network (SN; blue). After calculating average within-network connectivity values for each participant, partial correlations (corrected for age and gender) were performed between body composition data (BMI or BFP) and: (B) DMN connectivity, (C) ECN connectivity, and (D) SN connectivity. Neither measure of body composition was correlated with resting state DMN connectivity (panel B) or ECN connectivity (panel C) after correcting for multiple comparisons. However, both BMI and BFP were associated with marginally significant increases in SN connectivity (panel D; p_adj. = 0.07 and p_adj. = 0.09, respectively). All brain images are displayed in neurological orientation, and are in normalized MNI space.