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. 2016 Jun 14;10:234. doi: 10.3389/fnins.2016.00234

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Copyright © 2016 Figley, Asem, Levenbaum and Courtney.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Linear relationships between body composition (i.e., BMI and BFP) and white matter volume within previously-defined stereotaxic atlases of (A) default mode network (DMN), (B) executive control network (ECN), and (C) salience network (SN) white matter regions (Figley et al., 2015), corrected for age and gender. Higher BMI and BFP were associated with statistically significant decreases in white matter volume in both the DMN (panel A; p_adj. = 0.05 and p_adj. = 0.03, respectively) and SN (panel C; p_adj. = 0.05 and p_adj. = 0.02, respectively); and although the relationship between BMI and ECN white matter volume was not significant (panel B; p_adj. = 0.14), BFP was associated with significantly decreased ECN white matter volume (panel B; p_adj. = 0.05).