Figure 3.

Measures of % lean mass (top left), % fat mass (top right), and lean-to-fat mass ratio (bottom left). * indicates a significant change relative to control and intermittent feeding (IF) groups, and + indicates a significant difference from control and rapamycin groups. Change in body weight over the course of the experiment (bottom right). Both treatment conditions decreased body weight, with a similar magnitude of effect in the old animals, and a greater effect in IF young animals compared with rapamycin-treated animals. * indicates a significant decrease relative to control, and + indicates a significant difference from control and rapamycin.