Table 3.

End-of-life Pathology in Diabetic db/db Mice

	Male		Female
	Control Diet	Rapamycin Diet	Control Diet	Rapamycin Diet
Nonneoplasm	25	35	25	30
Suppurative inflammation	22 (61%)	26 (74%)	11 (29%)	18 (51%)
Glomerulonephritis	2	0	1	0
Other	1	9	13	12
Neoplasm	9	0***	9	4*
Neoplasm and nonneoplasm	2	0	4	1
Total	36	35	38	35

Note: *p < .05, ***p < .001 compared with control diet.