Table 1.
Baseline Demographic, Health, and Functional Characteristics of Participants
| Characteristic | Total Sample | Association With Gait Speed |
|---|---|---|
| Mean (SD) or N (%) | βs (p Value) | |
| n = 265 | ||
| Age (years) | 82.9 (2.7) | −0.22 (.0004) |
| Gait speed (m/s) | 0.9 (0.2) | |
| Muscle strength (N*m) | 81.5 (30.3) | 0.31 (<.0001) |
| BMI (kg/m2) | 27.5 (4.4) | −0.23 (.0002) |
| 3MS score | 92.8 (6.8) | 0.27 (<.0001) |
| CES-D score | 7.0 (6.4) | −0.19 (.0017) |
| Female | 152 (57%) | −0.17 (.0064) |
| White | 158 (60%) | −0.26 (<.0001) |
| Education < high school | 39 (15%) | 0.10 (.1024) |
| Diabetes | 73 (28%) | −0.22 (.0003) |
| Hypertension | 180 (68%) | −0.19 (.0020) |
| Stroke | 20 (8%) | −0.13 (.0347) |
| Total brain MR measure | ||
| WMH (median, IQR) | 0.0033 (0.0074) | −0.25 (<.0001) |
| Fractional anisotropy | 0.358 (0.014) | 0.16 (.0110) |
| Gray matter atrophy* | 0.280 (0.023) | 0.07 (.2505) |
Notes: 3MS = Modified Mini-Mental Status Examination; βs = standardized beta; BMI = body mass index; CES-D = Center for Epidemiologic Studies-Depression; IQR = interquartile range; MR = magnetic resonance; WMH = white matter hyperintensities.
*Volume of atrophy is calculated as gray matter volume divided by intracranial volume.