Figure 2.

Intermittent administration of rapamycin does not impair glucose or insulin tolerance. (A) Glucose and (B) insulin tolerance test on female C57BL/6J.Nia mice treated with either vehicle or rapamycin (2mg/kg) once every 5 days for 8 weeks (n = 7–10 vehicle, n = 10 rapamycin, two-tailed t test). Tests were performed 5 days after the last administration of either vehicle or rapamycin, at the conclusion of an overnight fast. Error bars represent standard error.