Figure 3.

Intermittent administration of rapamycin impacts body weight and composition. (A) Weight tracking of mice receiving vehicle or rapamycin (2mg/kg) once every 5 days (starting n = 10 vehicle-treated mice, 10 rapamycin-treated mice at 615 days of age). (B, C) Changes in weight and body composition after 5 months of intermittent administration of either vehicle or rapamycin (n = 15 vehicle-treated mice, 13 rapamycin-treated mice; p value shown for values between 0.05 and 0.1, two-tailed t test). Error bars represent standard error.