Table 2. Toxicity of amicoumacin A to human cell lines.
Cell line | C/NC* | IC50, μM (IC50, μg/ml) |
---|---|---|
A549 | C | 0,2 ± 0,1 (0,08 ± 0,04) |
MCF7 | C | 0,3 ± 0,1 (0,13 ± 0,04) |
HEK293T | NC | 0,55 ± 0,03 (0,23 ± 0,01) |
VA13 | NC | 1,2 ± 0,2 (0,51 ± 0,08) |
The cytotoxicity was assayed by the MTT test. The concentrations of amicoumacin A in the growth media that caused 50% growth inhibition or cell death (IC50) is presented in both μM and μg/ml scale.
*- ‘C’ – cancerous cell line; ‘NC’ – non-cancerous cell line.