Table 2. Functional annotation clusters identified by DAVID bioinformatics resource among “hits” enriched in cells that resist BCG infection.
| Category | Term | Count | P-value |
|---|---|---|---|
| Annotation Cluster 1 | Enrichment Score: 3.33 | ||
| SP_PIR_KEYWORDS | Oxidoreductase | 18 | 7.0 × 10−5 |
| GOTERM_BP_FAT | Oxidation reduction | 21 | 4.7 × 10−4 |
| GOTERM_MF_FAT | Electron carrier activity | 10 | 3.2 × 10−3 |
| Annotation Cluster 2 | Enrichment Score: 2.92 | ||
| GOTERM_MF_FAT | Protein dimerization activity | 20 | 1.4 × 10−4 |
| GOTERM_MF_FAT | Protein homodimerization activity | 13 | 2.0 × 10−3 |
| GOTERM_MF_FAT | Identical protein binding | 18 | 6.2 × 10−3 |
| Annotation Cluster 3 | Enrichment Score: 2.67 | ||
| GOTERM_CC_FAT | Membrane-bounded vesicle | 17 | 1.1 × 10−3 |
| GOTERM_CC_FAT | Cytoplasmic membrane-bounded vesicle | 16 | 2.2 × 10−3 |
| GOTERM_CC_FAT | Vesicle | 18 | 2.4 × 10−3 |
| GOTERM_CC_FAT | Cytoplasmic vesicle | 17 | 3.8 × 10−3 |
| Annotation Cluster 4 | Enrichment Score: 2.61 | ||
| GOTERM_BP_FAT | Inflammatory response | 14 | 5.3 × 10−4 |
| GOTERM_BP_FAT | Defense response | 18 | 4.6 × 10−3 |
| GOTERM_BP_FAT | Response to wounding | 16 | 6.2 × 10−3 |
| Annotation Cluster 5 | Enrichment Score: 2.11 | ||
| GOTERM_BP_FAT | RNA biosynthetic process | 13 | 7.8 × 10−4 |
| GOTERM_BP_FAT | Transcription, DNA-dependent | 12 | 2.3 × 10−3 |
| GOTERM_BP_FAT | Transcription from RNA polymerase II promoter | 10 | 4.9 × 10−3 |