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. 2016 Jun 14;6:27566. doi: 10.1038/srep27566

Table 3. “Hits” belonging to the oxidation-reduction functional cluster identified with DAVID bioinformatics resource.

Gene Symbol Definition Frequency BCGlow Frequency BCGhigh BCGlow/BCGhigh
NQO1 NAD(P)H dehydrogenase, quinone 1 43266 602 71.9
DHRS2 Dehydrogenase/reductase (SDR family) member 2 22344 324 68.9
CYP1B1 Cytochrome P450, family 1, subfamily B, polypeptide 1 21146 456 46.4
ACADS Acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain 15638 370 42.2
GLRX Glutaredoxin (thioltransferase) GRX1 13630 417 32.7
DMGDH Dimethylglycine dehydrogenase 11657 373 31.3
AKR1A1 Aldo-keto reductase family 1, member A1 (aldehyde reductase) 11551 674 17.1
IFI30 Interferon, gamma-inducible protein 30 11146 557 20.0
NSDHL NAD(P) dependent steroid dehydrogenase-like (NSDHL) 9820 626 15.7
PIWIL2 Piwi-like 2 (Drosophila) (PIWIL2) 9787 757 12.9
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23 kDa 8713 167 52.3
DHFR Dihydrofolate reductase 8530 1491 5.7
DPYD Dihydropyrimidine dehydrogenase 8387 528 15.9
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13 kDa 8011 931 8.6
HMOX2 Heme oxygenase (decycling) 2 (HMOX2) 6166 537 11.5
PPARGC1A Peroxisome proliferator-activated receptor gamma, coactivator 1α 5944 642 9.3
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42 kDa 5442 791 6.9
ETFA Electron-transfer-flavoprotein, alpha polypeptide 5362 1013 5.3
PRDX6 Peroxiredoxin 6 5160 822 6.3
SIRT7 Sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) 5058 979 5.2
UQCRH Ubiquinol-cytochrome c reductase hinge protein 4930 1172 4.2