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. 2016 Jun 14;6:27945. doi: 10.1038/srep27945

Figure 1. Novel set of acute kidney injury (AKI) related signature microRNAs (miRs) in the urine.

Figure 1

(A) Heat map showing miRs significantly altered in the urine of AKI patients. MiRs expression signatures were obtained from microarray analysis of control and patients in intensive care unit (ICU) with AKI. Number 5 and 6 indicated normal, 1, 2, 3 and 4 indicated AKI patients in ICU. (B) Real time polymerase chain reaction (qPCR) analysis of urinary miR-16 in control and ICU patients with AKI. (C) Serum miR-16 levels were normalized to U6 RNA. Serum miR-16 values differed significantly between the control and ICU patients with AKI or between ICU patients with and without AKI. (D) Urinary miR-16 was measured by qPCR and neutrophil gelatinase-associated lipocalin (NGAL) were measured by ELISA kit (BioVendor, Candler, USA) in the control and ICU patients with or without AKI. *P < 0.05, N.S., no significant difference.