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Interactions between 12 proteins of the RASopathies (PTPN11, SOS1, RAF1, BRAF, KRAS, NRAS, HRAS, MAP2K1, MAP2K2, SPRED1, NF1, and RIT1) associated with 6 RASopathy syndromes. Figure colors represent the following: black = reaction; blue = binding; green = activation; light green = expression; pink = post-translational modification; red = inhibition; violet = catalysis.
