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Synthesis of compounds 5 a–r, 6, and 7 a,b. Reagents and conditions: a) carboxylic acids, EDC⋅HCl, Et3N, DMF, 0 °C → rt; b) FeSO4⋅7 H2O, NH4OH, H2O, rt; c) Pd/C, H2, MeOH, rt. Reaction times, yields, and purities are summarized in Table S1 in the Supporting Information.
