Table 2.
ADH |
FEA |
LN |
RS |
PL |
Proportion of B3 |
Overall PML for B3 lesions |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PML | n/N* | PML | n/N | PML | n/N | PML | n/N | PML | n/N | % | n | PML | n/N | |
This study (2012) | 0.26 | 69/266 | 0.18 | 15/82 | 0.26 | 24/91 | 0.11 | 2/18 | 0.03 | 2/64 | 17.0% | 1532/9153 | 0.21 | 112/521 |
Bianchi, 2011 (7) | 0.27 | 197/721 | 0.12 | 31/245 | 0.22 | 83/377 | 0.10 | 14/132 | 0.13 | 18/135 | 11.9% | 3107/26,165 | 0.21 | 349/1644 |
Dillon, 2007 (8) | 0.35 | 14/40 | 0.40 | 4/9 | 0.17 | 9/54 | 0.18 | 5/28 | 5.7% | 211/3729 | 0.21 | 37/177 | ||
El-Sayed, 2008 (9) | 0.32 | 61/188 | 0.30 | 8/27 | 0.12 | 19/156 | 0.11 | 13/124 | 5.2% | 705/13,452 | 0.2 | 106/523 | ||
Hayes, 2009 (10) | 0.32 | 8/25 | 0.13 | 1/8 | 0.50 | 3/3 | 0.12 | 7/57 | 0.08 | 2/24 | 7.7% | 141/1829 | 0.16 | 22/141 |
Houssami, 2007 (6) | 0.45 | 63/141 | 0.61 | 14/23 | 0.17 | 7/42 | 0.23 | 10/44 | 9.2% | 372/4035 | 0.3 | 98/279 | ||
Lee, 2003 (11) | 0.46 | 13/28 | 0.66 | 6/9 | 0.20 | 5/25 | 0.15 | 3/20 | 3.0% | 116/3822 | 0.3 | 29/96 | ||
Lieske, 2008 (12) | 0.50 | 36/72 | 1.00 | 1/1 | 0.38 | 9/24 | 0.09 | 4/43 | 0.26 | 9/35 | 5.4% | 220/4080 | 0.34 | 67/199 |
Noske, 2010 (13) | 0.36 | 5/14 | 0.07 | 5/14 | 0.00 | 0/6 | 0.00 | 0/7 | 0.07 | 1/15 | 6.6% | 122/1854 | 0.1 | 881 |
n/N = count of malignant lesions after open resection (n) from the total of B3 lesions in the histopathological subdiagnosis (N).
ADH, atypical ductal hyperplasia; FEA, flat epithelial atypia; LN, lobular neoplasia; PL, papillary lesion; PML, proportion of malignant lesions; RS, radial scar; VABB, vacuum-assisted breast biopsy.