TABLE 2.
Ten SGA Neonates Classified as Having Severe and Persistent Thrombocytopenia of SGA
| Birth Weight, g | SGA Percentile | Gestational age at birth, wk/d | Maternal Preeclampsia, Eclampsia, or HELLP | Lowest platelet count in the first 2 wks after birth, /μL | Lowest platelet count at 4–6 weeks, /μL | Platelet Transfusions Received, n | Diagnosis at 4–6 wks | Outcome |
|---|---|---|---|---|---|---|---|---|
| 350 | <1st | 24/0 | None | 27 000 | 48 000 | 21 | Necrotizing enterocolitis with bowel resection | Died at 6 mo in NICU |
| 406 | <1st | 22/6 | HELLP | 42 000 | 30 000 | 33 | a | Died at home at 7 mo |
| 420 | <1st | 24/5 | HELLP | 52 000 | 23 000 | 31 | Candida sepsis | Died at home at 17 mo |
| 470 | <1st | 26/5 | Eclampsia | 46 000 | 40 000 | 8 | a | Lived |
| 480 | <1st | 23/6 | Preeclampsia | 49 000 | 38 000 | 11 | a | Lived |
| 510 | <1st | 26/4 | Preeclampsia | 36 000 | 36 000 | 8 | Klebsiella sepsis | Lived |
| 565 | <1st | 27/0 | HELLP | 121 000 | 47 000 | 10 | Necrotizing enterocolitis with bowel perforation and resection | Lived |
| 580 | <1st | 27/1 | None | 52 000 | 10 000 | 16 | Necrotizing enterocolitis with Enterobacter cloacae sepsis | Lived |
| 663 | <1st | 29/2 | None | 36 000 | 37 000 | 4 | a | Lived |
| 2100 | 10th | 35/1 | None | 73 000 | 12 000 | 8 | Complex congenital heart disease, Klebsiella sepsis | Died in hospice at 5 y |
Ten SGA neonates who were classified as having thrombocytopenia of SGA and, when tabulated 28 to 42 days after birth, were still severely thrombocytopenic (<50 000/µL) and receiving platelet transfusions. Six of the 10 had “late consumptive thrombocytopenia” and 4 had no explanation for persistent thrombocytopenia, other than thrombocytopenia of SGA.
a
No explanation, other than severe SGA, for severe thrombocytopenia continuing at 4 to 6 wks.