Table 4.
Special types of DEGs during SUS progression in A. japonicus
| Gene name | First sequencing | Re-sequencing | ||||
|---|---|---|---|---|---|---|
| SUS-I | SUS-II | SUS-III | SUS-I | SUS-II | SUS-III | |
| Attachment/Pathogen recognition | ||||||
| CLECT | −1.56 | −1.79 | −2.99 | −3.27 | −3.34 | −3.77 |
| CLECT isoform 3 | −1.69 | −2.01 | −2.21 | −3.27 | −3.23 | −3.64 |
| CLEC19A | −1.71 | −1.89 | −2.12 | −2.51 | −2.68 | −2.78 |
| GalNAc-specific lectin | −1.21 | −1.52 | −1.91 | −5.37 | −6.05 | −6.58 |
| lactose-binding lectin l-2-like | a | a | −1.29 | a | −2.96 | −3.24 |
| Fibrinogen-like protein A | −1.32 | −1.25 | −1.18 | −2.74 | −2.79 | −2.18 |
| SRCR protein | 3.47 | 3.62 | 3.91 | 5.32 | 5.27 | 5.68 |
| FNDC3A-like | 7.49 | 7.51 | 6.39 | 5.09 | 5.08 | 4.91 |
| Annexin A13 | 1.56 | 1.64 | 1.27 | 2.21 | 1.69 | 1.33 |
| Mucin-2 | 6.21 | 5.49 | 7.66 | 8.78 | 8.38 | 8.64 |
| Integrin alpha-1 | 2.14 | 1.85 | 1.8 | 3.80 | 3.20 | 3.23 |
| Integrin alpha-9-like | 4.6 | 4.02 | 5.08 | 5.45 | 4.77 | 4.65 |
| Integrin Alpha-Lv1 | 5.88 | 6.23 | 7.08 | 6.23 | 5.31 | 5.5 |
| Integrin beta-2 | 2.02 | 1.45 | 1.51 | 2.24 | 1.94 | 1.74 |
| Integrin beta-C subunit | 13.24 | 12.8 | 11.31 | 5.31 | 5.31 | 5.24 |
| Integrin beta G subunit precursor | 4.44 | 4.11 | 4.24 | 4.35 | 3.98 | 3.83 |
| Tenascin-R-like | −1.67 | −2.28 | −2.04 | −1.18 | −1.77 | −1.89 |
| Inflammation Reactions | ||||||
| Complement C3 | 2.82 | 2.93 | 3.15 | 3.68 | 3.55 | 3.39 |
| Complement component 3-2 | 6.63 | 6.42 | 6.5 | 3.49 | 3.15 | 3.29 |
| Complement Bf | 1.29 | 1.63 | 1.64 | 3.3 | 3.45 | 3.41 |
| Complement receptor type 2 isoform X1 | 2.71 | 3.43 | 2.87 | 3.42 | 4.25 | 3.51 |
| IgGFc-binding protein | 3.21 | 3.31 | 2.51 | 4.99 | 4.85 | 4.2 |
| Collagen alpha-1 (XI) chain-like | 5.12 | 5.27 | 5.11 | 5.99 | 5.91 | 5.81 |
| Collagen alpha-2 | 7.11 | 6.34 | 6.03 | 5.93 | 5.06 | 5.13 |
| Collagen alpha-5 | 4.51 | 3.62 | 3.31 | 5.02 | 4.52 | 4.06 |
| MyD88 | 1.36 | 1.38 | 1.54 | 1.60 | 1.64 | 1.75 |
| TRAF 1 | 2.29 | 2.63 | 2.69 | 4.02 | 4.1 | 4.42 |
| TRAF5-like | 5.46 | 7.65 | 5.94 | 2.44 | 2.93 | 2.57 |
| IRAK4-like | 3.65 | 3.57 | 3.91 | 3.7 | 3.09 | 2.86 |
| NF-kB transcription factor Rel | 3.25 | 3.78 | 3.48 | 3.64 | 4.11 | 3.91 |
| NF-kB p105 subunit | 3.45 | 3.54 | 3.82 | 4.17 | 4.22 | 4.4 |
| MAPKKK | 2.25 | 2.25 | 2.17 | 2.38 | 2.81 | 2.61 |
| Serine/threonine-protein kinase TBK1-like | 4.82 | 5.07 | 4.79 | 5.46 | 5.31 | 5.12 |
| Stress-activated protein kinase JNK-like | 4.24 | 4.21 | 4.33 | 3.89 | 3.63 | 4.02 |
| TGF beta-activated kinase | 2.89 | 2.98 | 2.96 | 4.35 | 4.21 | 4.53 |
| TOLLIP | 3.41 | 3.79 | 3.56 | 3.43 | 4.25 | 3.91 |
| Zonadhesin-like | 6.67 | 5.5 | 6.97 | 11.89 | 11.85 | 11.38 |
| IFI27-like protein 2 | −2.64 | −2.47 | −2.38 | −3.02 | −2.93 | −3.17 |
| Apolipoprotein B-100-like | 3.47 | 3.83 | 4.22 | 2.93 | 3.18 | 3.56 |
| Macrophage mannose receptor 1-like | 3.01 | 3.25 | 3.18 | 4.3 | 4.63 | 4.72 |
| Matrix metalloproteinase-9 | 5.72 | 4.84 | 5.42 | 8.41 | 7.71 | 8.15 |
| Matrix metalloproteinase-24 | 3.91 | 3.71 | 4.01 | 2.41 | 1.41 | 1.57 |
| Matrix metalloproteinase 24 preproprotein-like | 4.52 | 3.43 | 3.59 | 3.91 | 3.71 | 4.01 |
| Prostaglandin E synthase 2-like | 1.26 | 1.42 | 1.23 | 1.51 | 1.77 | 1.85 |
| Suppressor of cytokine signaling 2-like | 5.33 | 4.89 | 5.18 | 4.95 | 4.45 | 4.81 |
| Tumor protein p53-inducible protein 11-like | 2.34 | 2.59 | 2.26 | 4.23 | 4.79 | 4.42 |
| NFIL3 | 2.07 | 2.96 | 2.38 | 3.21 | 2.38 | 1.41 |
| TMPRSS 5-like | 10.34 | 10.37 | 10.79 | 10.39 | 10.41 | 10.83 |
| LENG8 homolog | 4.28 | 4.44 | 3.99 | 5.37 | 5.48 | 5.04 |
| IGDCC4-like | 3.76 | 3.08 | 3.15 | 1.87 | 1.95 | 1.88 |
| LIG-3 isoform 2 | 2.22 | 2.51 | 2.41 | 3.45 | 3.94 | 3.63 |
| Variable lymphocyte receptor | 2.02 | 2.27 | 2.28 | 9.74 | 11.04 | 11.26 |
| Thrombospondin-2 | 4.31 | 4.22 | 3.88 | 3.13 | 3.01 | 2.72 |
| Thrombospondin-3 | 5.28 | 5.08 | 5.31 | 4.77 | 4.49 | 4.86 |
| Major yolk protein | −2.63 | −2.51 | −2.13 | −3.07 | −3.03 | −3.45 |
| Oxidative Stress Response | ||||||
| HSP 70 | 3.84 | 5.24 | 5.09 | 3.76 | 5.17 | 5.06 |
| HSP 26 | 3.59 | 5.84 | 5.58 | 2.63 | 4.55 | 4.54 |
| HSP 110 | 2.08 | 1.63 | 1.73 | 3.33 | 2.96 | 3.26 |
| HSP 90 | 7.13 | 7.42 | 7.83 | 2.31 | 1.59 | 1.75 |
| Dual oxidase 1 | 4.36 | 4.27 | 4.41 | 4.82 | 4.54 | 4.65 |
| GPX1-like | 2.09 | 1.92 | 1.62 | 2.72 | 2.50 | 2.65 |
| Thioredoxin | 2.33 | 2.19 | 2.32 | 2.91 | 2.7 | 3.38 |
| Apoptosis/Autophagy/Lysosome/Phagosome | ||||||
| Apoptosis regulator BAX-like | 2.02 | 2.27 | 2.45 | 7.72 | 7.52 | 8.36 |
| Apoptosis-inducing factor 2-like | 2.08 | 2.14 | 1.99 | 2.21 | 2.48 | 2.01 |
| Calpain-5 | 2.65 | 2.64 | 2.08 | 4.77 | 4.79 | 4.20 |
| Calpain-7 | 1.96 | 1.94 | 1.99 | 3.06 | 3.12 | 3.08 |
| Caspase-6-like | 3.82 | 4.12 | 4.36 | 2.12 | 3.31 | 2.44 |
| Cyclophilin B | 1.97 | 1.96 | 1.91 | 1.90 | 2.03 | 2.30 |
| Cytochrome c-like | −1.14 | −1.32 | −1.22 | −1.65 | −1.84 | −1.75 |
| Cytochrome c oxidase subunit 7C | −2.06 | −1.95 | −1.95 | −2.57 | −2.65 | −2.76 |
| BFAR -like | 2.57 | 3.19 | 2.73 | 8.03 | 8.15 | 7.95 |
| Bcl-2 protein | 5.29 | 4.83 | 4.67 | 4.08 | 3.65 | 3.43 |
| Bcl-2-like protein 1-like | 2.25 | 2.58 | 2.32 | 4.04 | 4.34 | 4.14 |
| BIRC2 | 3.28 | 2.9 | 3.01 | 3.8 | 3.52 | 3.42 |
| BIRC 6-like | 3.18 | 3.17 | 2.96 | 5.06 | 5.11 | 4.89 |
| PDCD6IP -like | 2.17 | 2.17 | 2.22 | 3.61 | 3.77 | 3.69 |
| PDCD10 -like | 3.79 | 3.47 | 3.54 | 4.41 | 4.29 | 4.32 |
| DRAM 2-like | 2.38 | 2.54 | 2.95 | 3.93 | 4.24 | 4.19 |
| PDRG 1 | −2.83 | −2.83 | −1.83 | −3.81 | −3.51 | −3.13 |
| Exportin-1-like | 1.59 | 1.52 | 1.59 | 11.77 | 10.38 | 11.82 |
| Exportin-T | 1.37 | 1.49 | 1.61 | 1.64 | 1.42 | 1.59 |
| Cathepsin D | 7.13 | 7.47 | 7.44 | 6.13 | 7.16 | 8.09 |
| Cathepsin L | 1.72 | 1.83 | 1.79 | 3.18 | 3.84 | 4.71 |
| Cathepsin B-like protease | 3.08 | 3.19 | 3.25 | 3.23 | 3.37 | 3.57 |
| Lysozyme-like | −1.51 | a | −1.69 | −3.38 | a | −3.67 |
| Autophagy-related protein 2 homolog B | 6.46 | 6.31 | 5.79 | 3.82 | 4.29 | 3.75 |
| Lysosome membrane protein 2-like | 4.27 | 4.72 | 3.11 | 4.39 | 4.03 | 3.55 |
| Lysosomal alpha-mannosidase-like | 2.34 | 2.56 | 2.51 | 9.49 | 10.11 | 10.05 |
| Lysosomal-trafficking regulator-like | 1.92 | 1.51 | 1.43 | 4.85 | 4.68 | 4.7 |
| ADP-ribosylation factor-like 1 | 1.72 | 1.42 | 1.58 | 6.12 | 6.09 | 6.43 |
| ADP-ribosylation factor-like 3 | 2.32 | 1.51 | 2.68 | 4.25 | 4.61 | 4.52 |
| Beta-galactosidase-like | 1.66 | 1.42 | 1.78 | 4.11 | 4.01 | 3.61 |
ameans no significantly different in gene expression. The numbers in the Table represent Log2 fold change of I-SUS-BW/H-BW, II-SUS-BW/H-BW and III-SUS-BW/H-BW