Table I.
Characteristics of eligible patients.
| Characteristic | No. of patients (n=73) |
|---|---|
| Age (range) | 65 (39–80) |
| Gender | |
| Male | 58 (79%) |
| Female | 15 (21%) |
| ECOG performance status | |
| 0 | 41 (56%) |
| 1 | 29 (40%) |
| 2 | 3 (4%) |
| No. of previous chemotherapy regimens | |
| 2 | 40 (55%) |
| 3 | 21 (29%) |
| ≥4 | 12 (16%) |
| Objective response rate | |
| CR | 0 |
| PR | 11 (15%) |
| SD | 24 (33%) |
| PD | 35 (48%) |
| NE | 3 (4%) |
| Median progression-free survival (range), days | 77 (8–682) |
| Median overall survival (range), days | 228 (25–1058) |
ECOG, Eastern Cooperative Oncology Group; CR, complete response; PR, partial response; SD, stable disease; PD, progression disease; NE, not evaluated.