Table 1.
Clinical characteristics of the study population
| Cytology cohort | UroVysion FISH cohort | |
|---|---|---|
| Sample size | ||
| Unique subjects | 871 | 827 |
| Test-cystoscopy pairs | 4023 | 1696 |
| Age (years, median) | 66 (IQR: 56–75) | 67 (IQR: 56–76) |
| < 40 | 34 (4 %) | 29 (4 %) |
| 40–50 | 89 (10 %) | 84 (10 %) |
| 50–60 | 162 (19 %) | 152 (18 %) |
| 60–70 | 248 (29 %) | 227 (27 %) |
| 70–80 | 222 (26 %) | 217 (26 %) |
| ≥ 80 | 113 (13 %) | 118 (14 %) |
| Gender | ||
| Male | 540 (62 %) | 488 (59 %) |
| Female | 328 (38 %) | 339 (41 %) |
| Race | ||
| White | 668 (78 %) | 648 (78 %) |
| Black | 157 (18 %) | 154 (19 %) |
| Other | 26 (3 %) | 25 (3 %) |
| Smoking status | ||
| Current smoker | 75 (9 %) | 82 (10 %) |
| Former smoker | 403 (48 %) | 407 (49 %) |
| Never smoker | 356 (43 %) | 338 (41 %) |
| Indication for test | ||
| Hematuria | 415 (48 %) | 368 (44 %) |
| Urothelial carcinoma | 331 (38 %) | 322 (39 %) |
| Other | 125 (14 %) | 137 (17 %) |
| Cystoscopy result | ||
| Negative | 2783 (69 %) | 1324 (78 %) |
| Positive | 752 (19 %) | 185 (11 %) |
| Atypical/Suspicious | 492 (12 %) | 187 (11 %) |
| Urine test result | ||
| Negative | 1632 (41 %) | 1210 (71 %) |
| Positive | 375 (9 %) | 486 (29 %) |
| Atypical/Suspicious | 2016 (50 %) | - |
IQR interquartile range